Papers
Showing 154 published or preprint papers authored by the Bennett Institute.
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Association between living with children and outcomes from covid-19
Working on behalf of NHS England, this paper used the OpenSAFELY platform to investigate whether risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and outcomes of coronavirus disease 2019 (covid-19) differed between adults living with and without children during the first two waves of the UK pandemic.
Status: Published
Categories
- OpenSAFELY
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Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7
Working on behalf of NHS England, this paper uses the OpenSAFELY platform to estimate the risk of death following confirmation of SARS-CoV-2 infection in England, comparing infection with VOC to non-VOC, after accounting for demographic factors and comorbidities
Status: Published
Categories
- OpenSAFELY
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Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic
Working on behalf of NHS England, this study used the OpenSAFELY platform to describe the overall rate of various key clinical events over time, and their relationship with COVID-19.
Status: Preprint
Categories
- OpenSAFELY
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Short report: Ethnicity and COVID-19 death in the early part of the COVID-19 second wave in England
This short data report investigates whether there were ethic inequalities in COVID-19 death in the second wave in England.
Status: Preprint
Categories
- OpenSAFELY
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Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19
Working on behalf of NHS England, this paper used the OpenSAFELY platform to assess the association between routinely prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and deaths from COVID-19.
Status: Published
Categories
- OpenSAFELY
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HIV infection and COVID-19 death
Working on behalf of NHS England, this paper used the OpenSAFELY platform to investigate the association between HIV infection and COVID-19 mortality.
Status: Published
Categories
- OpenSAFELY
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Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality
Working on behalf of NHS England, this paper used the OpenSAFELY platform to investigate the effectiveness of hydroxychloroquine for prevention, as opposed to treatment, of COVID-19 mortality. We found no evidence of benefit or harm after adjusting for important differences between people with the same health conditions prescribed hydroxychloroquine or not.
Status: Published
Categories
- OpenSAFELY
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Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care
JMIR EHR design paper
Categories
- OpenPrescribing
- Policy Insights
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Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
This protocol reports details of a planned study to explore the extent to which incorporating time-varying measures of infection burden over time improves the quality of risk prediction models for COVID-19 death in a large population of adult patients in England.
Status: Preprint
Categories
- OpenSAFELY
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Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids
Working on behalf of NHS England, this paper used the OpenSAFELY platform to investigate the association between ICS and COVID-19-related death among people with COPD or asthma using linked electronic health records (EHRs) in England, UK.
Status: Published
Categories
- OpenSAFELY
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How we learnt to stop worrying and love web scraping
Nature web scraping article
Categories
- Open Working
- Research Integrity
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Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care
EHR design paper
Categories
- OpenPrescribing
- Research Integrity
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Prescription of suboptimal statin treatment regimens: a retrospective cohort study of trends and variation in English primary care
BJGP statins paper
Categories
- OpenPrescribing
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The NHS deserves better use of hospital medicines data
Hospitals Data BMJ Paper
Categories
- OpenPrescribing
- Policy Insights
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Bringing NHS data analysis into the 21st century
JRSM Paper on NHS Analytics
Categories
- Open Working
- Policy Insights
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Factors associated with COVID-19-related death using OpenSAFELY
Working on behalf of NHS England, this paper used the OpenSAFELY platform to quantify a range of clinical risk factors for COVID-19-related death in the largest cohort study conducted by any country to date.
Status: Published
Categories
- OpenSAFELY
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Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.
Describing trends and geographical variation in methotrexate prescribing that breaches national safety recommendation
Categories
- OpenPrescribing
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The poor performance of apps assessing skin cancer risk
BMJ Skin apps paper
Categories
- Policy Insights