1. COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.

    Identifying discrepancies in trial reporting in high-impact medical journals

    Categories

    • Research Integrity
  2. COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials

    Responses to correspondence highlighting discrepancies in trials reporting

    Categories

    • Research Integrity
  3. Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data.

    Reducing antibiotic overuse is a key NHS priority. The majority of antibiotics are prescribed in primary care

    Categories

    • OpenPrescribing
  4. Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data

    Measuring the impact of OpenPrescribing being viewed on subsequent prescribing.

    Categories

    • OpenPrescribing
  5. Why did some practices not implement new antibiotic prescribing guidelines on urinary tract infection? A cohort study and survey in NHS England primary care

    Describing trends and geographical variation in prescribing of trimethoprim and nitrofurantoin to treat urinary tract infections

    Categories

    • OpenPrescribing
    • Policy Insights
  6. Opioid prescribing trends and geographical variation in England, 1998–2018: a retrospective database study

    Our findings support calls for greater action to promote best practice in chronic pain prescribing and to reduce geographical variation.

    Categories

    • OpenPrescribing
  7. Six months on – NHS England needs to focus on dissemination, implementation and audit of its Low-Priority Initiative

    JRSM letter

    Categories

    • OpenPrescribing
  8. Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests

    BMJ Tests in primary care paper

    Categories

    • OpenPathology
  9. Too few trials or too few reported trials?

    Highlighting that there is a serious ongoing issue with the results of completed trials not being reported.

    Categories

    • Policy Insights
    • TrialsTracker
  10. Time trends and geographical variation in prescribing of antibiotics in England 1998–2017

    Despite a general trend towards more optimal antibiotic prescribing, considerable geographical variation persists across England's practices and CCGs.

    Categories

    • OpenPrescribing
  11. Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.

    Assessing compliance rates with the European Commission's requirement that all trials on the EU Clinical Trials Register (EUCTR) post results to the registry within 12 months of completion

    Categories

    • TrialsTracker
  12. Reply to Comment on 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'

    Replying to comment on paper: 'Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis'

    Categories

    • OpenPrescribing
  13. Why Cochrane should prioritise sharing data

    Discussing Cochrane's practice on data sharing.

    Categories

    • Open Working
    • Policy Insights
    • Research Integrity
  14. Detecting Change in Comparison to Peers in NHS Prescribing Data: a Novel Application of Cumulative Sum Methodology

    The CUSUM method appears to effectively discriminate between random noise and sustained change in prescribing behaviour. This method aims to allow practices and CCGs to be informed of important changes quickly, with a view to improve their prescribing behaviour.

    Categories

    • OpenPrescribing
  15. Pregabalin: what the patent litigation means for doctors and drug companies

    Explaining the arguments over the Pregabalin patent case and explore the wider implications for the NHS and drug development

    Categories

    • OpenPrescribing
  16. The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care

    Describing the variation in prescribing of pregabalin as branded Lyrica, geographically and over time

    Categories

    • OpenPrescribing
  17. Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care

    Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen.

    Categories

    • OpenPrescribing
  18. Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017

    Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.

    Categories

    • OpenPrescribing