Papers
Showing 154 published or preprint papers authored by the Bennett Institute.
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Measuring BMI in 22 million patients in England
This study describes the use of four derivations of BMI in OpenSAFELY.
Status: Published
Categories
- OpenSAFELY
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Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic
Amongst adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common amongst females, younger adults, those living in more deprived areas, and those with mental health conditions.
Status: Published
Categories
- OpenSAFELY
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Safety of direct-acting oral anticoagulant (DOAC) prescribing
This study aimed to identify the proportion of those prescribed a DOAC with recorded: weight, estimated Glomerular Filtration Rate (eGFR), creatinine, creatinine clearance (CrCl) and atrial fibrillation (AF). In those with recorded AF and CrCl prescribed the study aimed to identify the proportion with a recommended DOAC dose.
Status: Published
Categories
- OpenSAFELY
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OpenSAFELY: a platform for analysing electronic health records designed for reproducible research
This paper describes OpenSAFELY's reproducibility-by-design approach in detail.
Status: Published
Categories
- OpenSAFELY
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Trends in inequalities in avoidable hospitalisations across the COVID-19 pandemic
We determine whether periods of disruption were associated with increased ‘avoidable’ hospital admissions and wider social inequalities in England.
Status: Published
Categories
- OpenSAFELY
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net
A low cost randomised trial of an educational intervention in CCGs to influence prescribing of low-priority items
Status: Preprint
Categories
- OpenPrescribing
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Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease
Cohort study investigating whether ursodeoxycholic acid was associated with COVID-19 related hospitalisation and death in people with primary biliary cirrhosis and primary sclerosing cholangitis.
Status: Preprint
Categories
- OpenSAFELY
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Impact of COVID-19 on mental illness in vaccinated and unvaccinated people
This study examined associations of COVID-19 with subsequent mental illness in the pre-vaccination period of the pandemic and for unvaccinated and vaccinated people after vaccination became available.
Status: Preprint
Categories
- OpenSAFELY
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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic
Germ Defence is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively reduce the spread of COVID-19, the intervention needed to be implemented at scale rapidly.
Status: Published
Categories
- OpenSAFELY
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Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic
We used OpenSAFELY-TPP data to elucidate the association between non-Covid-19 related sepsis and a range of risk factors during the Covid-19 pandemic
Status: Published
Categories
- OpenSAFELY
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Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research
A short data report about comparators in pathology test results
Status: Published
Categories
- OpenSAFELY
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Antibiotics for Common Infections in Primary Care Before, During and after the COVID-19 Pandemic and Extent of Risk-Based Prescribing: Need for Personalised Guidelines
We assessed the changes in risk-based prescribing behaviours of antibiotics for common infections in primary care during the Covid-19 pandemic
Status: Preprint
Categories
- OpenSAFELY
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The impact of the COVID-19 pandemic on the treatment of common infections in primary care and the change to antibiotic prescribing in England
We studied how antibiotic precribing for common infections in primary changed duding the Covid-19 pandemic and how this may have affected clincial outcomes
Status: Published
Categories
- OpenSAFELY
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Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home
We describe the impact of the the COVID-19 pandemic on antipsychotic prescribing in those with autism, dementia, learning disability, serious mental illness or living in a care home.
Status: Published
Categories
- OpenSAFELY
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Effect of the 2022 COVID-19 booster vaccination campaign in 50 year olds in England
This study evaluated the effectiveness of the 2022 autumn COVID-19 booster campaign in 50 year olds in England using a regression discontinuity design.
Status: Preprint
Categories
- OpenSAFELY
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Challenges in Estimating the Effectiveness of 2 Doses of COVID-19 Vaccine Beyond 6 Months in England
This paper discusses the challenges in estimating long-term (>6 months) vaccine effectiveness in observational data, primarily due to high uptake of a subsequent third vaccine dose.
Status: Published
Categories
- OpenSAFELY
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Gout incidence and management during the COVID-19 pandemic in England, UK
Assessing how the COVID-19 pandemic impacted incidence and quality of care for people with gout in England, UK.
Status: Published
Categories
- OpenSAFELY
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Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway
The pandemic affected healthcare in England across the pancreatic cancer pathway. Positive lessons could be learnt from the services that were resilient and those that recovered quickly
Status: Published
Categories
- OpenSAFELY