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OpenSAFELY blog posts

  3. Posted
    Categories
    • OpenSAFELY

    We won an MRC award for open science

    Most of the time, we like to keep things fairly formal on this blog - but if you’ll forgive us a small indulgence, today we’re going to blow our own trumpet a little. A couple of weeks ago, my colleague Rose Higgins and I went to an event in London where this Institute was awarded the Open Science Impact award, as part of the MRC Impact Prize. We were, needless to say, over the moon about it.

  4. Posted
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    • OpenSAFELY

    Research-ready computers in the cloud

    Spend more time answering your research questions – and less time wrangling your computer – with GitHub Codespaces and the OpenSAFELY development container.

  8. Posted
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    • OpenSAFELY

    DMARD monitoring during the COVID-19 pandemic

    We describe some of our recent work investigating the impact of the COVID-19 pandemic on DMARD safety monitoring across >24 million patients’ records in England.

  19. Posted
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    • OpenSAFELY

    How we test ehrQL

    How can you be confident that the queries you write will be correctly interpreted and return the expected results?

  22. Posted
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    • OpenSAFELY

    Understanding Repeat Antibiotic Prescribing in the Pandemic: Insights On Health Inequalities

    The COVID-19 pandemic has reshaped many aspects of healthcare, including how antibiotics are prescribed in primary care settings. In this guest blog, Professor Diane Ashiru-Oredope lead pharmacist for antimicrobial resistance at UK Health Security Agency and our own Brian MacKenna, share some insights on repeat antibiotic prescribing and the link to health inequalities from a recent UK Health Security Agency analysis using OpenSAFELY.

  24. Posted
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    • OpenSAFELY

    Updates of OpenSAFELY Research on COVID-19 Therapeutics

    In this guest blog, Bang Zheng and Laurie Tomlinson from the London School of Hygiene and Tropical Medicine describe some of their lastest work on the comparative effectiveness and safety of currently recommended COVID-19 therapeutics in the community settings.

  30. Posted
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    • OpenSAFELY

    Why ehrQL?

    Why did we create a new query language?

  32. Posted
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    • OpenSAFELY

    OpenSAFELY Service Restoration Observatory: Key Measures

    In this blog, we describe the development of a set of key measures used to monitor the ongoing impact of the COVID-19 pandemic on primary care as part of the OpenSAFELY Service Restoration Observatory (SRO). The results from this work have now been published in eLife.

  37. Posted
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    • OpenSAFELY

    OpenSAFELY for Impact: COVID-19 Therapeutics

    Millie and Laurie share how some of the outputs from the work on COVID-19 therapeutics have been used to inform policy and guidelines in the NHS and beyond.

  39. Posted
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    • OpenSAFELY

    Introduction to the Product Team

    The OpenSAFELY Product Team’s mission is to understand our users’ needs, identify opportunities to improve OpenSAFELY products, and work with the tech teams to figure out the best solutions to build. Who are we? Catherine Stables is Lead Product Manager. In her previous role she was Data Product Manager for DataLoch, based at the University of Edinburgh. She has a background in academic research on cardiovascular disease, and a PhD from King’s College London.

  41. Posted
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    • OpenSAFELY

    The Opensafely Output Checking Service

    An outline the OpenSAFELY output checking service: who it involves, how our output checkers are trained and an overview of the output checking workflow.

  42. Posted
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    • OpenSAFELY

    Introduction to the Pipeline Team

    Introducing the Bennett Institute’s Pipeline team, where we talk about who we are, what we do and some of the products we’re responsible for.

  44. Posted
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    • OpenSAFELY

    Introduction to the Epidemiology Team

    Here we introduce the Bennett Institute’s Epidemiology team, explaining who they are, what they do, and why it is important.

  46. Posted
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    • OpenPrescribing

    Introduction to the Clinical Informatics Team

    Here we introduce the Bennett Institute’s Clinical Informatics team, explaining what they do and how their experience in NHS clinical practice helps them do this.

  47. Posted
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    • OpenSAFELY

    Introduction to the Data Team

    Hello, from the Bennett Institute’s Data Team! In this short blog post, we’ll describe our mission, our backgrounds in industry and academia, and what we’re working on now.

  51. Posted
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    • OpenSAFELY

    OpenSAFELY Research Highlights

    Here we outline some of the research that has been produced with OpenSAFELY, as well as the features that make it such a great platform for research.

  53. Posted
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    • OpenSAFELY

    OpenSAFELY NHS Service Analytics

    On 7th May 2020, the OpenSAFELY Collaborative pre-printed the world’s largest study into factors associated with death from COVID-19, based on an analysis running across the full pseudonymised health records of 40% of the English population.

  55. Posted
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    • OpenSAFELY

    Using electronic health records and open science in the COVID-19 pandemic

    We recently presented on behalf of our team (grp-EHR) at an open science workshop, hosted by the MRC Biostatistics Unit at the University of Cambridge. This was a great opportunity for us to reflect on our team’s experiences using OpenSAFELY, and more broadly embracing open and team science approaches to our work.

  56. Posted
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    • OpenSAFELY

    An Update on Our Co-piloting Programme: What's New?

    As a team of co-pilots, we regularly take time to discuss how co-piloted projects are going and what we can do to help pilots and co-pilots make the most of their time together.

  57. Posted
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    • OpenSAFELY

    Conducting Research Using OpenSAFELY: My Experience of the Co-pilot Service

    Rachel Seeley is the Head of Analytics at PrescQIPP CIC and has recently completed a project in OpenSAFELY on the safer use of anticoagulant medication. In this guest blog, Rachel describes her experience with using the OpenSAFELY platform and our co-pilot programme.

  59. Posted
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    • OpenPrescribing

    OpenPrescribing June 2022 Newsletter

    Our latest newsletter including information on: Bennett Institute for Applied Data Science, we are recruiting, Goldacre Review, updated Outlier Dashboards, recent changes to OpenPrescribing Measures, OpenSAFELY news, and new data news.

  60. Posted
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    • OpenSAFELY

    Invitation: CIPHA-OpenSAFELY Introduction Event

    CIPHA and OpenSAFELY are hosting an introduction event for researchers in the North West of England who would like to work with CIPHA data using OpenSAFELY.

  61. Posted
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    • OpenSAFELY

    Closing the STEM gap is a collective responsibility

    Our policy lead, Jess Morley, discusses the challenges involved in closing the gap in representation and reward for women working in these fields, and what we in the Bennett Institute are trying to do to help lower some of the associated barriers.

  62. Posted
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    • OpenPrescribing

    OpenPrescribing December Newsletter

    Our latest newsletter including information on: We are recruiting, recent changes to OpenPrescribing Measures, new Outlier Prescribing tool, maps update, recent research publications, OpenSAFELY news, and new data news.

  63. Posted
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    • OpenSAFELY

    First Impressions of a New Start

    I joined Bennett Institute in August 2021 to work as a data scientist on OpenSAFELY. This blog post describes my experience getting up and running with the OpenSAFELY pipeline.

  66. Posted
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    • OpenSAFELY

    OpenSAFELY: Public Opinion

    This week sees the publication of an independent Citizens’ Jury commissioned for NHSx and the National Data Guardian which found that OpenSAFELY was by far the most strongly and consistently supported of all NHS COVID data projects examined.

  67. Posted
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    • OpenSAFELY

    OpenSAFELY: The Origin Story

    On our first anniversary, from the Policy Lead in the Bennett Institute, this is the brief story of the positive side from all our lives: how OpenSAFELY came to life, and what we’ve achieved so far.

  68. Posted
    Categories
    • Open Working

    Citing and Crediting Codelists: A discussion for the research community

    This is a draft discussion paper, the first of a series exploring “open team science” approaches to managing health data, and specifically how to create a collaborative computational data science ecosystem where the sharing and re-use of objects such as codelists and code is facilitated, encouraged, recognised, and rewarded. As a microcosm of this we have first explored “codelists”. There are currently no ‘answers’ or preferred solutions given. We will be holding an open discussion with the research community on 2nd March at 3pm - you can book to join us here.

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    • OpenPrescribing

    OpenPrescribing Newsletter November 2020

    We have been very busy since our last newsletter back in July and there are tonnes of exciting updates for you here! Measure Update: Total Oral Morphine Equivalence The Faculty of Pain Medicine has recently updated their recommendation on oral morphine equivalence (OME) which we use on our OpenPrescribing measure of OME. We have taken this opportunity to update and a new novel implementation of how we assess OME. Until this work is completed we have taken the decision to “suspend” the measure from dashboards however you can still view the old method using this link.

  70. Posted
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    • Code

    OpenSAFELY Cohort Extractor

    This is the code for the OpenSAFELY cohort extractor tool which supports the authoring of OpenSAFELY-compliant research, by: Allowing developers to generate random data based on their study expectations. They can then use this as input data when developing analytic models. Supporting downloading of codelist CSVs from the OpenSAFELY codelists repository, for incorporation into the study definition Providing tools to understand and visualise the properties of real data, without having direct access to it It is also the mechanism by which cohorts are extracted from live database backends within the OpenSAFELY framework.

  71. Posted
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    • Code

    OpenSAFELY Job Runner

    This is the repository for the OpenSAFELY job runner. A job runner is a service that encapsulates: the task of checking out an OpenSAFELY study repo; executing actions defined in its project.yaml configuration file when requested via a jobs queue; and storing its results in a particular locations. The documentation is aimed at developers looking for an overview of how the system works. It also has some parts relevant for end users, particularly the project.

  72. Posted
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    • Code

    OpenSAFELY Job Server

    This is the code for the OpenSAFELY job server designed for mediating jobs that can be run in an OpenSAFELY secure environment. The Django app provides a simple REST API which provides a channel for communicating between low-security environments (which can request that jobs be run) and high-security environments (where jobs are run).

  73. Posted
    Categories
    • Open Working

    What is OpenSAFELY?

    What is OpenSAFELY? Working on behalf of NHS England we have now built a full, open source, highly secure analytics platform running across the full pseudonymised primary care records of 24 million people, rising soon to 55 million, 95% of the population of England. We have pursued a new model: for privacy, security, low cost, and near-real-time data access, we have built the analytics platform inside the EHR data centre of the major EHR providers, where the data already resides; in addition we have built software that uses tiered increasingly non-disclosive tables to prevent researchers ever needing direct access to the disclosive underlying data to run analyses; code is developed against simulated data using open platforms before moving to the live data environment.

  74. Posted
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    • Open Working

    OpenPrescribing July Newsletter

    OpenPrescribing and Bennett Institute Papers It has been a busy month for paper publication at The Bennett Institute. We have written a brief description of the most recent papers below. Please sharewith colleagues and get in touch if you have any relevant observations! Remember you can read all our academic papers related to OpenPrescribing on our research page. Hospital medicines data: We are frequently contacted at OpenPrescribing about when we are going to make a hospital version.

  75. Posted
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    • Open Working

    OpenPrescribing June Newsletter

    Methotrexate Prescribing Safety — New paper in BJGP This week the British Journal of General Practice published our latest paper on unsafe prescribing of methotrexate. We found that the prevalence of unsafe methotrexate prescribing (10mg tablets) has reduced but remains common, with substantial variation between practices and CCGs. In the paper we also discuss recommendations for better strategies around implementation. Anyone can view the live data on unsafe methotrexate prescribing at openprescribing.

  76. Posted
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    • Open Working

    OpenPrescribing Newsletter May 2020

    OpenSAFELY.org OpenSAFELY is a new secure analytics platform for electronic health records in the NHS, created to deliver urgent results during the global COVID-19 emergency. OpenSAFELY is a collaboration between the Bennett Institute, the EHR group at London School of Hygiene and Tropical Medicine and TPP who produce SystmOne. OpenSAFELY is now successfully delivering analyses across more than 24 million patients’ full pseudonymised primary care NHS records. The first analysis from OpenSAFELY is Factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients with more answers to important questions expected shortly.

  77. Posted
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    • OpenSAFELY

    Impact of COVID-19 on prescribing in English general practice: March 2020

    OpenPrescribing.net has been updated this week with the latest release of prescribing data covering March 2020. In-depth analysis will be needed over the coming months, but this release gives us the first glimpse into the impact that COVID-19 has had on prescribing. At the Bennett Institute we have been quite busy with the new secure analytics platform OpenSAFELY but the following blog is a rapid analysis of the March prescribing data which others may find helpful to focus their own investigations.